Changes in levels of BNP, CRP and leukocyte formula during exercise testing in patients with dilated cardiomyopathy

Results During exercise testing have been increasing BNP (246.98 ± 571.74 vs. 257.91 ± 473.47 ng/L, p=0.002), CRP (3.83 ± 5.04 vs. 4.14 ± 5.25 mg/L, p=0.016) and WBC count (8.01 ± 1.83 vs. 10.61 ± 2.54x109/L, p<0.001). Increased the number of neutrophils (4.80 ± 1.42 vs. 5.85 ± 1.89 x 109/L, p<0.001), lymphocytes (2.30 ± 0.72 vs. 3.50 ± 1.15 x 109/L, p<0.001), eosinophil (0.20 ± 0.16 vs. 0.26 ± 0.24 x 109/L, p<0.001), monocytes (0.65 ± 0.22 vs. 0.88 ± 0.29 x 109/L, p<0.001) and basophils (0.01 ± 0.04 vs. 0.04 ± 0.01 x 109/L, p<0.029). Twelve months after the exercise test found significantly higher BNP levels (163.93 ± 266.05 vs. 279 ± 416.58 ng/L, p=0.002) , whereas CRP (3.93 ± 5.28 vs. 3.03 ± 2.82 mg/L) and WBC (8.05 ± 1.92 vs. 7.84 ± 1.81 x 109/L) did not change significantly in comparison to baseline values. Conclusions During exercise testing in patients with DCM there was a significant increase in the level of BNP, CRP, and all parameters of leukocyte formula.